Over-the-counter migraine remedies can be bought without a prescription from a doctor. Over-the-counter medications, also called nonprescription drugs, are considered safe and effective for people to use without direct guidance from a physician. 1 I am writing this based on 30 years of my own experience of reducing migraine headaches sans medicines. So, this is a proven method, which can be used by all migraine-affected people, with zero side effects. It depends on the cause of your headache. In my experience, it will do nothing for a migraine but will work well for a sinus headache. A tension headache will fall somewhere between the two, while it will have an indirect and beneficial effect on a headache caused by ‘flu. Meilleure réponse: Definitly, always use it when I have a headache and it always Works! For many people suffering from migraine headaches, over-the-counter ibuprofen -- Advil and Motrin are well-known brands -- might be enough to relieve the pain. A new Cochrane review finds that. In general, migraine treatment with medicines should be limited as much as possible when you're pregnant or breastfeeding. Instead, trying to identify and avoid potential migraine triggers is often recommended. User Reviews for Ibuprofen to treat Headache Also known as: Advil, Genpril, IBU, Midol IB, Motrin IB, Proprinal, Smart Sense Children's Ibuprofen The following information is NOT intended to endorse drugs or recommend therapy. In fact, ibuprofen, along with a similar NSAID, naproxen, are among the medications most often used for migraine pain, according to the America Migraine Foundation: They often are just as effective as other migraine medications, such as triptans, and also cost less and are less likely to lead to what is called the chronification of headaches. Migraine headaches are among the symptoms of an actual condition known as migraine. Some medications can ease the pain and symptoms of a migraine headache. Control your migraines before they control you. Advil® Migraine is clinically proven to relieve migraine pain and related symptoms, like nausea and sensitivity to light and sound.